About: http://www.idref.fr/040805638/id

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An Entity of Type : skos:Concept, within Data Space : data.idref.fr associated with source document(s)

Attributes	Values
type	Concept
seeAlso	http://www.idref.fr/064819582/id http://www.idref.fr/040807959/id
sameAs	http://id.nlm.nih.gov/mesh/D015536
notation	G02.111.240 G05.308.200 G07.690.773.937
alternative label	Down Regulation Downregulation Down-Regulation Down-Regulation (Physiology) Down-Regulation, Receptor Receptor Down-Regulation Régulation négative (physiologie) Régulation négative des récepteurs
preferred label	Régulation négative
is in scheme	http://id.nlm.nih.gov/mesh
note	A negative regulatory process that decreases ligand-receptor interactions. Reduction in receptor binding after ligand exposure can result from the internalization of ligand-receptor complex, an increase in receptor degradation, and/or a decrease in gene expression resulting in a decrease in receptor biosynthesis A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins
is seeAlso of	http://www.idref.fr/040807959/id
is primary topic of	http://www.idref.fr/040805638
is Subject of	http://www.sudoc.fr/002910136/id http://www.sudoc.fr/132323125/id Physiologie des régulations http://www.sudoc.fr/161266568/id http://www.sudoc.fr/138021791/id Analyse de nouveaux régulateurs de la voie de transduction du signal IMD chez Drosophila melanogaster http://www.sudoc.fr/248002449/id Modulation de l'autophagie lors de la réactivation de l'EBV par le TGF β1 http://www.sudoc.fr/247130729/id http://www.sudoc.fr/247093149/id Les tétraspanes LEPROT et LEPROTL1, 2 nouveaux régulateurs négatifs de la sensibilité cellulaire à l'hormone de croissance http://www.sudoc.fr/269869662/id http://www.sudoc.fr/264723821/id

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