Cells found throughout the lining of the GASTROINTESTINAL TRACT that contain and secrete regulatory PEPTIDE HORMONES and/or BIOGENIC AMINES
Intestinal L cells are located in the MUCOSA of distal ILEUM and COLON. They secrete GLUCAGON-like peptides (GLP-1 and GLP-2), and peptide tyrosine tyrosine (PYY or PEPTIDE YY)
These cells produce SECRETIN and are found in the MUCOSA of upper SMALL INTESTINE and PYLORIC ANTRUM in mammals. Secretin also has been found in cells in the BRAIN and other tissues