About: Michel Khrestchatisky

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An Entity of Type : foaf:Person, within Data Space : data.idref.fr associated with source document(s)

Attributes	Values
type	Person
sameAs	Khrestchatisky, Michel Khrestchatisky, Michel Khrestchatisky, Michel Khrestchatisky, Michel
preferred label	Khrestchatisky, Michel
name	Michel Khrestchatisky
dbpedia-owl:citizenship	http://sws.geonames.org/3017382/
Language	http://lexvo.org/id/iso639-3/fra
isni:identifierValid	000000035764909X
Given name	Michel
familyName	Khrestchatisky
note	Directeur de thèse Chercheur au CNRS - Université Louis Pasteur - Strasbourg 1 en 2000 Chercheur. Directeur du Laboratoire de Neurobiologie des Interactions cellulaires et neurophysiopathologie, UMR 6184. Responsable d'équipe à l'IFR Jean Roche. Université de la Méditerranée, Marseille. Chercheur Aix Marseille Université à l'Institut Neurophysiopathologie. Codirecteur d'une thèse en Sciences Chimiques à Aix-Marseille en 2020
gender	male
ORCID iD	0000-0003-4797-8332
is sameAs of	Khrestchatisky, Michel Khrestchatisky, Michel Khrestchatisky, Michel
is Thesis advisor of	http://www.sudoc.fr/053698010/id http://www.sudoc.fr/167517635/id http://www.sudoc.fr/167597000/id http://www.sudoc.fr/193511428/id http://www.sudoc.fr/193153793/id Mise en place de modèles in vitro de barrière hémato‐encéphalique et étude du transfert transendothélial de vecteurs et conjugués ciblant le récepteur au LDL http://www.sudoc.fr/198629982/id Implication de MMP-2 dans les propriétés des cellules engainantes de la muqueuse olfactive et dans la réparation des lésions de la moelle épinière, études in vitro et in vivo http://www.sudoc.fr/060105658/id http://www.sudoc.fr/144363569/id http://www.sudoc.fr/198707886/id Trafic intracellulaire de peptide-vecteurs ciblant le récepteur au LDL pour des stratégies de délivrance ciblée d'agents thérapeutiques ou d'imagerie à travers la barrière hémato-encéphalique http://www.sudoc.fr/04386970X/id http://www.sudoc.fr/221542744/id http://www.sudoc.fr/271985046/id ETUDE DES EFFETS DU FBFB SUR LE DEVELOPPEMENT DES NEURONES D'HIPPOCAMPES EN CULTURE ET SON ROLE DANS LA REGULATION DES PROTEINES DU CYTOSQUELETTE http://www.sudoc.fr/23618119X/id http://www.sudoc.fr/247170984/id Distribution, trafic et sécrétion vésiculaire des MMPs et de leurs inhibiteurs dans les cellules neurales http://www.sudoc.fr/246582456/id Les apo-dystrophines dans le système nerveux central, analyse régional et développementale. Interactions et rôle potentiel dans l'architecture des synapses glutamatergiques http://www.sudoc.fr/260095311/id http://www.sudoc.fr/259991317/id http://www.sudoc.fr/246489243/id Les récepteurs au glutamate de type NMDA, étude de leur expression au cours du développement et dans deux modèles animaux d'épilepsie ; étude des relations structure/fonction et des interactions avec les protéines à domaines PDZ http://www.sudoc.fr/24580479X/id
is Praeses of	http://www.sudoc.fr/235975540/id
is Author of	http://www.sudoc.fr/096335246/id Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL Receptor Mapping of domains on HIV envelope protein mediating association with calnexin and protein-disulfide isomerase. Target engagement and intracellular delivery of mono- and bivalent LDL receptor-binding peptide-cargo conjugates: Implications for the rational design of new targeted drug therapies A unique method for the isolation of nasal olfactory stem cells in living rats Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus Involvement of tissue inhibition of metalloproteinases-1 in learning and memory in mice. Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury. Dérivés peptidiques et leur utilistion comme vecteurs de molécules sous forme de conjugués Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions. From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro Syngeneic Transplantation of Olfactory Ectomesenchymal Stem Cells Restores Learning and Memory Abilities in a Rat Model of Global Cerebral Ischemia Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017 LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion. Isolation and characterization of olfactory ecto-mesenchymal stem cells from eight mammalian genera Vesicular Trafficking and Secretion of Matrix Metalloproteinases-2, -9 and Tissue Inhibitor of Metalloproteinases-1 in Neuronal Cells Grafts of olfactory stem cells restore breathing and motor functions after a rat spinal cord injury Endogenous and synthetic MMP inhibitors in CNS physiopathology Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activities Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery The Human Nose Harbors a Niche of Olfactory Ectomesenchymal Stem Cells Displaying Neurogenic and Osteogenic Properties Use of LDL receptor-targeting peptide vectors for in vitro and in vivo cargo transport across the blood-brain barrier. Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention? http://www.sudoc.fr/259566691/id Structure et expression, au cours de la régénération traumatique, d'un gène α actine du muscle squelettique du pleurodè, implications évolutives et fonctionnelles Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting. Cholecalciferol (vitamin D₃) improves myelination and recovery after nerve injury Identification of LRP-1 as an endocytosis and recycling receptor for B1-integrin in thyroid cancer cells Tissue inhibitor of metalloproteinases-1 (TIMP-1) modulates neuronal death, axonal plasticity, and learning and memory. High and low permeability of human pluripotent stem cell–derived blood–brain barrier models depend on epithelial or endothelial features Transient increase of tenascin-C in immature hippocampus: astroglial and neuronal expression TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier. Cholecalciferol (vitamin D-3) improves functional recovery when delivered during the acute phase after a spinal cord trauma MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid ă pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model LDLR-mediated targeting and productive uptake of siRNA-peptide ligand conjugates in vitro and in vivo The human nose harbors a niche of olfactory ectomesenchymal stem cells displaying neurogenic and osteogenic properties Isolation and characterization of olfactory ecto-mesenchymal stem cells from eight mammalian genera Developmental vitamin D deficiency alters learning in C57Bl/6J mice Global cerebral ischemia in rats leads to amnesia due to selective neuronal death followed by astroglial scar formation in the CA1 layer The FVB/N mice: A well suited strain to study learning and memory ă processes using olfactory cues Métalloprotéases et leurs inhibiteurs dans la Maladie d'Alzheimer et les autres maladies neurodégénratives https://hal.archives-ouvertes.fr/hal-02283035#id MT5-MMP, just a new APP processing proteinase in Alzheimer's disease? TWEAK is expressed at the cell surface of monocytes during multiple sclerosis. Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood-brain barrier Role of Matrix Metalloproteinases in Migration and Neurotrophic Properties of Nasal Olfactory Stem and Ensheathing Cells

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