About: Jean-Sébastien Saulnier-Blache

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An Entity of Type : foaf:Person, within Data Space : data.idref.fr associated with source document(s)

Attributes	Values
type	Person
sameAs	Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....)
Life Event	http://www.idref.fr/060144130/birth
preferred label	Saulnier-Blache, Jean-Sébastien (19..-....)
name	Jean-Sébastien Saulnier-Blache
Language	http://lexvo.org/id/iso639-3/fra
isni:identifierValid	0000000356549302
Given name	Jean-Sébastien
familyName	Saulnier-Blache
has biographical i...tion (Deprecated)	Directeur de recherche membre de l'Institut des Maladies Métaboliques et Cardiovasculaires (I2MC) de l'Université Toulouse 3 Paul Sabatier (UT3) et de l'Institut national de la santé et de la recherche médicale (Inserm) (en 2020)
note	Directeur de recherche, responsable du laboratoire de contrôle du développement du tissu adipeux blanc par les catécholamines et l'acide lysophosphatique, INSERM, Toulouse (en 2001)
ORCID iD	0000-0002-8971-7723
ISI Researcher ID	X-7729-2018
Scopus ID	7003424775
is sameAs of	Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....) Saulnier-Blache, Jean-Sébastien (19..-....)
is Thesis advisor of	Obésité, fibrose du tissu adipeux, gluco-intolérance, un nouveau médiateur lipidique impliqué, l'acide lysophosphatidique http://www.sudoc.fr/182233839/id The role of LPA in kidney pathologies http://www.sudoc.fr/182055914/id http://www.sudoc.fr/16413686X/id http://www.sudoc.fr/053778979/id http://www.sudoc.fr/060144742/id http://www.sudoc.fr/164089969/id Les sécrétions du tissu adipeux, rôles de l'autotaxine et recherche de nouvelles adipokines http://www.sudoc.fr/122411528/id http://www.sudoc.fr/122822730/id Etude de la régulation et du rôle de l'autotaxine et de l'acide lysophosphatidique dans le tissu adipeux et le rein http://www.sudoc.fr/228330475/id http://www.sudoc.fr/228331838/id REGULATION 2-ADRENERGIQUE DU CYTOSQUELETTE DANS LES PREADIPOCUYTES, IMPLICATION DE RHOA L'analyse protéomique du liquide amniotique, une clé pour améliorer la compréhension des mécanismes du développement rénal et des maladies associées Etude de la réceptivité adrénergique et de la production d'acide lysophosphatidique par le tissu adipeux humain http://www.sudoc.fr/248059521/id http://www.sudoc.fr/255542690/id http://www.sudoc.fr/247021857/id http://www.sudoc.fr/248010883/id http://www.sudoc.fr/246520302/id http://www.sudoc.fr/255578245/id http://www.sudoc.fr/246582782/id
is Author of	http://www.sudoc.fr/009424245/id Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease Depot-specific regulation of autotaxin with obesity in human adipose tissue. Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis. Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression. Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization. http://id.erudit.org/iderudit/008986ar#id Mapping of the amniotic fluid proteome of fetuses with congenital anomalies of the kidney and urinary tract identifies plastin 3 as a protein involved in glomerular integrity Lysophosphatidic acid-1-receptor targeting agents for fibrosis. Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. Acide lysophosphatidique : un nouveau lien entre plaquettes sanguines et métastases osseuses Hepatic oval (stem) cell expression of endothelial differentiation gene receptors for lysophosphatidic acid in mouse chronic liver injury. Ca(2+)-independent phospholipase A2 is required for alpha2-adrenergic-induced preadipocyte spreading. Hepatocyte nuclear factor‐1β shapes the energetic homeostasis of kidney tubule cells Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence. In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue. Régulations neuro-humorales de l'expression du récepteur alpha2-adrénergique, étude sur l'adipocyte mature et le préadipocyte chez le hamster, [thèse en partie soutenue sur un ensemble de travaux] LPA as a paracrine mediator of adipocyte growth and function. Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production. The CKD plasma lipidome varies with disease severity and outcome https://serval.unil.ch/notice/serval:BIB_4D727712F436#id https://hal.archives-ouvertes.fr/inserm-03237054#id Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activity. https://hal.archives-ouvertes.fr/hal-03268501#id Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression. Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2. The low affinity p75 neurotrophin receptor is down-regulated in congenital anomalies of the kidney and the urinary tract: Possible involvement in early nephrogenesis Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D. http://www.sudoc.fr/245499687/id Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes. Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid. Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase. Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease Connectivity mapping of glomerular proteins identifies dimethylaminoparthenolide as a new inhibitor of diabetic kidney disease A simple and highly sensitive radioenzymatic assay for lysophosphatidic acid quantification. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth. Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity. Lysophosphatidic acid and renal fibrosis. Endothelial differentiation gene-2 receptor is involved in lysophosphatidic acid-dependent control of 3T3F442A preadipocyte proliferation and spreading. [Lysophosphatidic acid: a "bioactive" phospholipid] LPA1 receptor activation promotes renal interstitial fibrosis. Gbeta gamma-independent coupling of alpha2-adrenergic receptor to p21(rhoA) in preadipocytes. https://serval.unil.ch/notice/serval:BIB_BA696E2C41F3#id Lysophosphatidic acid synthesis and release. http://id.erudit.org/iderudit/010764ar#id https://serval.unil.ch/notice/serval:BIB_808A257804D2#id [Secretion and role of autotaxin and lysophosphatidic acid in adipose tissue]
is primary topic of	http://www.idref.fr/060144130
is Opponent of	Impact du transfert de tissu adipeux et de cellules souches mésenchymateuses sur le risque carcinologique http://www.sudoc.fr/192794493/id http://www.sudoc.fr/192802887/id

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