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An Entity of Type : skos:Concept, within Data Space : data.idref.fr associated with source document(s)

AttributesValues
type
sameAs
notation
  • EC 2.3.1.48
  • D08.811.913.050.134.415.500.049
  • D12.776.260.103.562
  • D12.776.930.125.562
  • D12.644.360.138.100
  • D12.776.476.156.200
alternative label
  • CLOCK Protein
  • CLOCK Proteins
  • Circadian Locomoter Output Cycles Kaput Proteins
  • Circadian Locomotor Output Cycles Kaput Proteins
  • Protéines horloges
preferred label
  • Protéines CLOCK
is in scheme
note
  • Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins
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