About: G-Quadruplex DNA   Goto Sponge  NotDistinct  Permalink

An Entity of Type : rdac:C10001, within Data Space : data.idref.fr associated with source document(s)

AttributesValues
type
alternative label
  • G-quadruplex DNA, methods and protocols
dc:subject
  • DNA
  • ADN
  • Life Sciences
  • Biochemistry
  • Transférase terminale
  • Cytology
  • Cell Biology
  • Human Genetics
  • Telomerase
  • Life sciences
  • Biochemistry, general
  • Cell biology
  • Human genetics
  • Quadruplex nucleic acids
  • G-quadruplexes
preferred label
  • G-Quadruplex DNA
Language
Subject
dc:title
  • G-Quadruplex DNA
note
  • Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In G-Quadruplex DNA: Methods and Protocols, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, G-Quadruplex DNA: Methods and Protocols promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA
dc:type
  • Text
http://iflastandar...bd/elements/P1001
rdaw:P10219
  • 2010
has content type
is primary topic of
is rdam:P30135 of
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