About: Prefoldins: the new chaperones

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An Entity of Type : rdac:C10001, within Data Space : data.idref.fr associated with source document(s)

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type	frbr:Work rdac:C10001
dc:subject	Conformation des protéines Chaperons moléculaires Cancer research Cell biology Biochemistry. Molecular biology Molécules chaperonnes Medicine. Proteins Protein Science. Human Genetics. Oncology. Cell Biology. Cytology. Cancer Research. Protéines -- Conformation Human genetics. Molecular Medicine. Protein Structure. Pliage des protéines Protéines du choc thermique
preferred label	Prefoldins: the new chaperones
Language	http://lexvo.org/id/iso639-3/eng
Subject	http://www.idref.fr/04071652X/id http://www.idref.fr/034111964/id http://www.idref.fr/030784697/id http://www.idref.fr/040766616/id http://www.idref.fr/040822362/id http://www.idref.fr/040833763/id
dc:title	Prefoldins: the new chaperones
note	This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease. This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined. This work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.
dc:type	Text
http://iflastandar...bd/elements/P1001	http://iflastandards.info/ns/isbd/terms/contentform/T1009
rdaw:P10219	2018
has content type	http://rdaregistry.info/termList/RDAContentType/1020
is primary topic of	http://www.idref.fr/234333634
is rdam:P30135 of	http://www.sudoc.fr/23247494X/id http://www.sudoc.fr/234323558/id

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