About: Emmanuel Lemichez

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An Entity of Type : foaf:Person, within Data Space : data.idref.fr associated with source document(s)

Attributes	Values
type	Person
sameAs	Lemichez, Emmanuel (19..-....) Lemichez, Emmanuel (19..-....) Lemichez, Emmanuel (19..-....) Lemichez, Emmanuel (19..-....)
Life Event	http://www.idref.fr/087117673/birth
preferred label	Lemichez, Emmanuel (19..-....)
name	Emmanuel Lemichez
dbpedia-owl:citizenship	http://sws.geonames.org/3017382/
Language	http://lexvo.org/id/iso639-3/eng http://lexvo.org/id/iso639-3/fra
isni:identifierValid	0000000043033428
Given name	Emmanuel
familyName	Lemichez
has biographical i...tion (Deprecated)	Directeur de recherche à l'INSERM U627, IFR 50, Faculté de Médecine, Nice (en 2005). Directeur de thèse. directeur de recherche à l'INSERM et directeur de l'Unité \"Toxines Bactériennes\" à l'Institut Pasteur de Paris, Université Paris Cité (en 2023)
gender	male
ORCID iD	0000-0001-9080-7761
Scopus ID	56020355800
is sameAs of	Lemichez, Emmanuel (19..-....) Lemichez, Emmanuel (19..-....)
is Thesis advisor of	http://www.sudoc.fr/198614586/id http://www.sudoc.fr/097539562/id Leishmaniose à Leishmania infantum, portage asymptomatique, vaccination par voie endonasale et apport de la bioluminescence http://www.sudoc.fr/221581413/id http://www.sudoc.fr/16828703X/id http://www.sudoc.fr/156471876/id http://www.sudoc.fr/168284081/id http://www.sudoc.fr/168690047/id http://www.sudoc.fr/223723134/id http://www.sudoc.fr/137616422/id http://www.sudoc.fr/236137395/id Étude des relations fonctionnelles entre les toxines CNF1 et alpha-hémolysine (HlyA) des Escherichia coli uropathogènes Ect2 MgcRacGAP, Deux régulateurs des RhoGTPases dont l'expression dépend du cycle cellulaire http://www.sudoc.fr/246872543/id http://www.sudoc.fr/254467822/id Mécanismes moléculaires et biologiques des facteurs d'invasion CNF1 de Escherichia coli et EDIN de Staphylococcus aureus http://www.sudoc.fr/247982385/id http://www.sudoc.fr/247127248/id http://www.sudoc.fr/270255362/id Étude des effets cytotoxiques du facteur létal de Bacillus anthracis sur l'endothélium http://www.sudoc.fr/282462228/id
is Author of	http://www.sudoc.fr/049563092/id Bacillus sphaericus binary toxin elicits host cell autophagy as a response to intoxication Screening in Planarians Identifies MORN2 as a Key Component in LC3-Associated Phagocytosis and Resistance to Bacterial Infection Microbial pathogenesis meets biomechanics Conformational Insights into the Control of CNF1 Toxin Activity by Peptidyl-Prolyl Isomerization: A Molecular Dynamics Perspective Decrease of Staphylococcus aureus Virulence by Helcococcus kunzii in a Caenorhabditis elegans Model Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery. Oxytocin Controls Differentiation of Human Mesenchymal Stem Cells and Reverses Osteoporosis. http://hub.abes.fr/edp/periodical/medsci/2012/volume_28/issue_1/medsci2012281p39/w Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination High prevalence of encoding RhoA-targeting toxin in clinical isolates of Staphylococcus aureus Posttranslational modifications of Rho GTPases mediated by bacterial toxins and cellular systems Transcellular tunnel dynamics: Control of cellular dewetting by actomyosin contractility and I-BAR proteins Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1 EDIN-B Promotes the Translocation of Staphylococcus aureus to the Bloodstream in the Course of Pneumonia MID-INFRARED SPECTROSCOPY HAS A HIGH SENSITIVITY AND SPECIFICITY FOR POINT-OF-CARE DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. Escherichia coli α-Hemolysin Counteracts the Anti-Virulence Innate Immune Response Triggered by the Rho GTPase Activating Toxin CNF1 during Bacteremia Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection TOXINE DIPHTERIQUE ET FACTEUR CYTOTOXIQUE NECROSANT (CNF1), MECANISMES D'INTERNALISATION ET MODE D'ACTION INTRACELLULAIRE Oxytocin controls differentiation of human mesenchymal stem cells and reverses osteoporosis. The cnf1 gene is associated with an expanding Escherichia coli ST131 H 30Rx/C2 subclade and confers a competitive advantage for gut colonization http://www.sudoc.fr/246433116/id Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation Escherichia coli Producing CNF1 Toxin Hijacks Tollip to Trigger Rac1-Dependent Cell Invasion Inhibition of the GTPase Rac1 Mediates the Antimigratory Effects of Metformin in Prostate Cancer Cells Switching Rho GTPase activation into effective antibacterial defenses requires the caspase-1/IL-1beta signaling axis Cross-Reactivity of Anthrax and C2 Toxin: Protective Antigen Promotes the Uptake of Botulinum C2I Toxin into Human Endothelial Cells Force-induced transcellular tunnel formation in endothelial cells ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells. CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion Adaptation of Staphylococcus aureus in a Medium Mimicking a Diabetic Foot Environment Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration CNF1-induced Ubiquitylation and Proteasome Destruction of Activated RhoA Is Impaired in Smurf1 −/− Cells Genetic Diversity and Population Structure of Leishmania infantum from Southeastern France: Evaluation Using Multi-Locus Microsatellite Typing Docosahexaenoic fatty acid-containing phospholipids affect plasma membrane susceptibility to disruption by bacterial toxin-induced macroapertures UBTD1 is a mechano‐regulator controlling cancer aggressiveness https://hal.archives-ouvertes.fr/pasteur-03380368#id IRSp53 senses negative membrane curvature and phase separates along membrane tubules ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion. Urinary interleukin-8 is elevated in urinary tract infections independently of the causative germs. Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro. C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus DHA-containing phospholipids control membrane fusion and transcellular tunnel dynamics Caveolae govern plasma membrane mechanics to protect cells against EDIN B-induced transcellular tunnel formation and lethality from S. aureus septicaemia In Silico Conformational Features of Botulinum Toxins A1 and E1 According to Intraluminal Acidification Bacterial toxins activating Rho GTPases. http://id.erudit.org/iderudit/006487ar#id Identification of adipocytes as target cells for Leishmania infantum parasites Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin. Parvimonas micra , an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

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