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n5http://id.nlm.nih.gov/mesh/
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n6http://id.nlm.nih.gov/
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EC 1.14.14.1 D12.776.422.220.453.915.099 D08.244.453.915.099 D12.776.422.220.453.489.500 D08.244.453.489.500 D08.811.682.690.708.170.447.500 D08.811.682.690.708.170.915.099
skos:altLabel
CYP 19 Cytochrome P450 19 CYP19 Cytochrome P450arom Aromatase, Androstenedione Aromatase CYP19 Protein Estrogen Synthetase Androstenedione Aromatase Protein, CYP19 Cytochrome P 450 CYP19 Cytochrome P-450(AROM) Cytochrome P-450 CYP19 P450AROM Estrogen Synthase
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Aromatase
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An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system